Page Output Caching and Proxy Servers

ASP.NET is your presentation layer (or should be); it consists of pages, user controls, server controls (HttpHandlers and HttpModules), and the content that they generate. If you have an ASP.NET page that generates output, whether HTML, XML, images, or any other data, and you run this code on each request and it generates the same output, you have a great candidate for page output caching.
By simply adding this line to the top of your page

<%@ Page OutputCache VaryByParams="none" Duration="60" %> 

you can effectively generate the output for this page once and reuse it multiple times for up to 60 seconds, at which point the page will re-execute and the output will once be again added to the ASP.NET Cache. This behavior can also be accomplished using some lower-level programmatic APIs, too. There are several configurable settings for output caching, such as the VaryByParams attribute just described. VaryByParams just happens to be required, but allows you to specify the HTTP GET or HTTP POST parameters to vary the cache entries. For example, default.aspx?Report=1 or default.aspx?Report=2 could be output-cached by simply setting VaryByParam="Report". Additional parameters can be named by specifying a semicolon-separated list. Many people don't realize that when the Output Cache is used, the ASP.NET page also generates a set of HTTP headers that downstream caching servers, such as those used by the Microsoft Internet Security and Acceleration Server or by Akamai. When HTTP Cache headers are set, the documents can be cached on these network resources, and client requests can be satisfied without having to go back to the origin server.
Using page output caching, then, does not make your application more efficient, but it can potentially reduce the load on your server as downstream caching technology caches documents. Of course, this can only be anonymous content; once it's downstream, you won't see the requests anymore and can't perform authentication to prevent access to it.